The Instruct Biennial Structural Biology Conference (IBSBC) showcased the latest in integrative structural biology from leading scientists across the world.
The 5th Instruct Biennial Structural Biology Conference was held at Utrecht in the Netherlands, from 19 - 20 May 2022. The theme of the 2022 conference was:
The conference explored new cutting-edge developments in structural biology, including the emerging methods and technologies that are helping scientists to decipher complex biomolecular dynamics.
Follow @instructhub on Twitter and tweet about the conference using #IBSBC2022
Instruct-ERIC is the single point of access to technology and expertise for structural biology research. Through its specialist research centres in Europe, Instruct-ERIC offers funded research visits, training, internships and R&D awards. By promoting integrative methods, Instruct-ERIC enables excellent science and technological development for the benefit of all life scientists.
Friedrich Foerster
University of Utrecht - Netherlands
José María Carazo
CNB-Madrid
Malene Ringkjøbing Jensen
Institut de Biologie Structurale
Jan Stayaert
Vrije Universiteit Brussel - Belgium
Ilaria Ferlenghi
Glaxosmithkline Vaccines - Italy
Marcin Nowotny
International Institute of Molecular and Cell Biology - Poland
Maya Topf
University of London, United Kingdom
Harald Schwalbe
University of Frankfurt, Germany
Montserrat Bárcena
Leiden University Medical Center, Netherlands
Juri Rappsilber
Institute of Biotechnology, Technische Universität Berlin, Germany
Wolfgang Baumeister
Max Planck Institute, Germany
Ora Schueler-Furman
Hebrew University, Israel
Peijun Zhang
Division of Structural Biology, Oxford University, UK
Ben Schuler
Department of Biochemistry, University of Zurich, Switzerland
Cristina Paulino
University of Groningen, Netherlands
Wei Yang
NIDDK, Maryland, USA
Katja Petzold
Karolinska Institute, Sweden
Giulia Zanetti
University of London, UK
Philipp Selenko
Weizmann Institute of Science, Israel
Tassos Perrakis
Netherlands Cancer Institute
Hugo Van Ingen
Utrecht University, Netherlands
Liang Xue
EMBL Heidelberg, Germany
David Zapletal
CEITEC, Czech Republic
Giorgia Fiorini
University of Oxford, UK
Agata Misiaszek
EMBL Heidelberg, Germany
Ida de Vries
Netherlands Cancer Institute
Ioannis Skalidis
Martin Luther Universität, Germany
Harald Schwalbe
Instruct-ERIC Director
All conference registrants are eligible to present a poster on integrative structural biology at IBSBC2022.
Additionally, the Scientific Organising Committee invited a small number of the submitted abstracts for an oral presentation.
Abstract specification: maximum one A4 page, including the title, author(s) and author affiliation(s), and up to one image.
Poster specification: A0 size, portrait orientation.
Registration for the Instruct Biennial Structural Biology Conference 2022 is closed.
The registration fee covers conference attendance, refreshments including lunch and gala dinner.
Download and sign in to the Whova conference app here - the official conference app for the Instruct Biennial
Find the full programme, abstract booklet, venue information and network with other attendees!
Instruct-ERIC Centres
Chairs: Marcin Nowotny and Friedrich Foster
| Time (CET) | Speaker Name | Speaker Institution | Talk Title |
| 9:00 - 9:10 | Tanja Kulkens | NWO | Instruct-ERIC Biennial Inauguration |
| 9:10 - 9:35 | Professor Harald Schwalbe | Instruct-ERIC Director | News from Instruct and how we can contribute to the development of anti-virals against SARS-CoV-2 |
| 9:40 - 10:05 | Professor Ben Schuler | University of Zurich, Switzerland | Probing the interaction dynamics of intrinsically disordered proteins with single-molecule spectroscopy Presentation |
| 10:10 - 10:35 | Dr Katja Petzold | Karolinska Institute, Sweden | RNA Dances: How structural changes define function |
| 10:40 - 11:05 | Tea / Coffee | ||
| 11:05 - 11:30 | Professor Ora Furman | Dept. of Microbiology and Molecular Genetics, IMRIC | Peptide binding as monomer complementation - new approaches for blind global high-resolution peptide docking Presentation |
| 11:35 - 12:00 | Dr Wei Yang | NIDDK, USA | Choreography of DNA during V(D)J recombination Presentation |
| 12:05 - 12:20 | Professor Wolfgang Baumeister | Max Planck Institute | Presentation of the Ivano Bertini Award award by Bruker and Wolfgang Baumeister |
| 12:20 - 12:45 | Bertini Award Winner, Sjors Scheres | Sjors Scheres Ivano Bertini Award Win Talk Presentation |
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| 12:45 - 14:00 | Break for Lunch |
Chairs: Malene Ringkjobing Jensen and Jose Maria Carazo
| Time (CET) | Speaker Name | Speaker Institution | Talk Title |
| 14:00 - 14:25 | Professor Cristina Paulino | University of Groningen, Netherlands | Shooting with electrons to unravel the mechanism of membrane transporters Presentation |
| 14:30 - 14:50 | Ida de Vries | The Netherlands Cancer Institute | AlphaFill: Enriching the AlphaFold models with ligands and co-factors Presentation |
| 14:55 - 15:20 | Dr Giulia Zanetti | University of London, UK | Membrane trafficking studied by cryo-electron tomography Presentation |
| 15:20 - 15:50 | Tea / Coffee | ||
| 15:50 - 16:10 | Giorgia Fiorini | University of Oxford | Mechanistic Studies on Human Prolyl Hydroxylase 2 Presentation |
| 16:15 - 16:35 | David Zapletal | CEITEC - Masaryk University | Cryo-EM reveals the structural basis for the regulatory function of HEL1 domain in vertebrate DICERs Presentation |
| 16:40 - 17:00 | Hugo van Ingen | Bijboet Center - Utrecht University | Chaperoning of the histone octamer by the acidic domain of DNA repair factor APL Presentation |
| 17:00 - 18:00 | Poster Session (Even Numbered Posters) | ||
| 18:00 - 19:00 | Poster Session (Odd Numbered Posters) | ||
| 20:00 | Conference Gala dinner |
Chairs: Jan Steyaert
| Time (CET) | Speaker Name | Speaker Institution | Talk Title |
| 9:00 - 9:25 | Professor Jury Rappsilber | University of Berlin, Berlin | In-cell analysis of protein-protein interactions by crosslinking mass spectrometry |
| 9:30 - 9:55 | Professor Peijun Zhang | University of Oxford, Oxford | Study virus assembly in cells by cryoEM Presentation |
| 10:00 - 10:25 | Dr Montserrat Barcena | Leiden University Medical Centre, Netherlands | The macromolecular landscape of nidovirus replication organelles Presentation |
| 10:30 - 11:00 | Tea / Coffee | ||
| 11:00 - 11:20 | Agata Misiaszek | EMBL Heidelberg | Cryo-EM structures of human RNA polymerase I Presentation |
| 11:25 - 11:50 | Anastassis Perrakis | Netherlands Cancer Institute | Deciphering the mechanism of microtubules detyrosination: from genetics to structures and back again Presentation |
| 11:55 - 12:20 | Liang Xue | EMBL Heidelberg | Delineating the bacterial translation machinery with unprecedented detail using cryo-ET and sub-tomogram analysis Presentation |
| 12:25 - 12:40 | Group Photo | ||
| 12:40 - 14:00 | Break for Lunch |
Chairs: Ilaria Ferlenghi
| Time (CET) | Speaker Name | Speaker Institution | Talk Title |
| 14:00 - 14:20 | Ioannis Skalidis | Martin Luther University Halle-Wittenberg | Cryo-EM and artificial intelligence visualize endogenous protein community members Presentation |
| 14:25 - 14:50 | Professor Philipp Selenko | Weizmann Institute, Israel | A blueprint for the Structural Biology department of the future Presentation |
| 14:50 - 15:20 | Professor Wolfgang Baumeister | Max Planck Institute of Biochemistry, Germany | Cryo-Electron Tomography or The Power of Seeing The Whole Picture Presentation |
| 15:25 - 16:00 | Poster prize presentation and Closing |
Student Fellowship applications are invited from graduate students. Fellowships will cover economy travel costs plus accommodation for 2 nights.
Eligibility requirements:
The Ivano Bertini Award recognises a significant achievement in frontier research that utilises an integrative structural biology approach. The Award commemorates Ivano Bertini, who developed powerful new methods in NMR and built up a world class Centre for Magnetic Resonance (CERM) in Florence. CERM was in the first group of major Centres in structural biology to form the core structure of Instruct-ERIC.
The Award of €15,000 is endowed by Bruker BioSpin which, together with Ivano, developed instrumentation to broaden the application of NMR and increase measurement sensitivity.
The Winner of the 2022 Ivano Bertini Award was Sjors Scheres of the MRC Structural Biology Lab in Cambridge, UK. Find out more about Sjors and their research here.
Muntgebouw Utrecht is a monumental location in the heart of Utrecht, regularly used for conferences, meetings, events and more.
Muntgebouw Utrecht
Leidseweg 90,
3531 BG Utrecht, Netherlands
Below are the hotels associated with the Biennial, which can be booked as accommodation by delegates for the event. Please note that due to several other concurrent events in Utrecht, hotels will be booked quickly, so it is recommended that accommodation is booked as soon as possible after registration.
NH Utrecht - Visit Website - €159 per night including breakfast
Crowne Plaza - Visit Website - €130 per night including breakfast
Park Plaza - Visit Website - €149 per night including breakfast
Regular trains travel between Utrecht Train Station and Schiphol Airport - 30 min journey time. Muntgebouw Utrecht is situated 1km from the from the Utrecht Central Station.
Confidentiality and use of information
All material presented at the IBSBC2022, including abstracts, oral presentations and posters, must be treated as personal communication and should be cited only with the consent of the author.
Photography or video/audio recording of oral presentations or individual posters is strictly prohibited unless with explicit consent of the meeting organisers and the author.
The content of abstracts, oral and poster presentations are the responsibility of the author(s). Instruct will publish the content of the submitted abstracts without asking for explicit consent from the author(s).
Filming and Photography
Filming and photography will be taking place at the event. Read our Filming and Photography Privacy Policy for more information.
Privacy Policy
Your personal data will be handled in accordance with the Instruct-ERIC Privacy Policy.
Cancellation Policy
Any circumstances beyond the reasonable control of Instruct (force majeure) requires to cancel the event, Instruct will notify the participants of such event without undue delay. Instruct will take reasonable steps to minimise the consequences of the force majeure such as reschedule, change from in person to virtual or shorten (in all cases partially or wholly) the Biennial and any performance related to it.
For termination of contract concerning an event between Instruct and the participant due force majeure, this shall be without any liability for either party, except in so far as has accrued prior to the date on which the termination of the contract takes effect.
Each party to the contract concerning the event shall itself be responsible for all direct and indirect financial consequences affecting it as a result of or in connection with the force majeure. The occurrence of force majeure shall not entitle either party to any additional payment or compensation.
In the event of a cancellation due to force majeure, Instruct will reimburse a participant registered for the cancelled event any payment made to Instruct for participation in such event. Refunds are issued if the Biennial is cancelled by Instruct. The reimbursement shall concern only payments made to Instruct for participation and shall exclude for this purpose any other costs committed by participants or associated with their attendance such as any travel, accommodation etc.
Social Media
We encourage participants to blog, tweet or otherwise communicate about the meeting (#IBSBC2022). However, dissemination of results or discussion presented at the meeting to anonymous third parties must obtain permission from the presenting author BEFORE communicating any results or discussion to third party groups, message boards, blogs or other online resources (other than your own lab or departments).
If you have specific questions regarding these issues or any other aspects of the conference, please contact the IBSBC2022 organising team.
Please submit any enquiries using the form below. Alternatively, you can email support@instruct-eric.org or call +44 1865 98 86 39 to speak with one of the Instruct-ERIC Hub Team.
